Nicotine affects the brain by binding to brain chemical receptors and increasing the release of brain chemicals, including (brain chemical), norepinephrine, and serotonin, leading to an increase in synaptic activity. This results in feelings of pleasure, complete awakeness and awareness, and improved mood. Over time, long-lasting exposure to nicotine can lead to changes in the brain's synaptic networks and affect the way the brain functions, leading to (state of being dependent on a drug) and possibly adding/giving to other brain-related problems.
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