Question

Consider the partial sequence of a peptide. ILWANRMSHVLFAVEA Select all amino acid residues likely to be on the solvent exposed surface once the peptide folds into its native conformation. Hint: Amino acids with nonpolar, or hydrophobic, side chains are generally in the interior of proteins. They do not come into contact with the aqueous solvent. L W Uu A N R M S H V > F E J

Answer 1

Polar and charged amino acids will be on the surface of a soluble protein, while non-polar amino acids will be in the interior. In the given partial sequence of the peptide ILWANRMSHVLFAVEA, the amino acid residues likely to be on the solvent exposed surface are L, W, A, N, R, M, S, H, V, F, and E.

Step-by-step explanation:

Polar and charged amino acids will be found on the surface of a soluble protein, while non-polar amino acids will be found in the interior. In the given partial sequence of the peptide ILWANRMSHVLFAVEA, the following amino acid residues are likely to be on the solvent exposed surface once the peptide folds into its native conformation: L, W, A, N, R, M, S, H, V, F, and E. These amino acids have polar and charged side chains or are polar and uncharged, making them more likely to interact with the aqueous solvent.