The answer to this question is: The most likely option for the mice to not breed is option (B) which is the river separated one species of mice into different species
The explanation of the above answer is as follows
The two populations having identical genes cannot breed because the river becomes the environmental barrier. There is no way for the mice to cross the river to the other side. Due to this reason, there is reproduction isolation for the mice. Therefore, the river separated one species of mice into two different ones and became the environmental barrier.