Answer:
Galactosemia is an inherited genetic disorder that affects the metabolism of the sugar galactose
Step-by-step explanation:
A lack of the enzyme galactose-1-phosphate uridyltransferase is what causes the condition (GALT). The long arm of chromosome 9 contains the gene that causes this condition, and it is inherited in an autosomal recessive manner.
In order for a child to be affected with galactosemia, the child must inherit two copies of the mutated gene, one from each parent. If Patricia and Les are both carriers of the mutated gene, each of their children will have a 25% chance of inheriting two copies of the gene and being affected with galactosemia. If Patricia and Les have another child, the probability that they will have a daughter that is affected with galactosemia is 1/4 or 0.25
It's vital to understand that this likelihood depends on Patricia and Les both having the mutant gene; if one of them didn't, the likelihood would vary. For them to learn more about their risk and the potential for their kid to be affected, genetic counseling before and after conception may be a useful alternative.