The Electoral College favors states with large numbers of electoral votes because the number of electoral votes allocated to each state is determined by the state's population. The more people living in a state, the more electoral votes that state is allocated. This means that states with larger populations have a proportionally greater influence in the election than states with smaller populations. For example, a state with a population of 10 million people will have more electoral votes than a state with a population of 1 million people.
In practice, this means that states with larger populations, such as California and Texas, have more electoral votes and therefore more influence in the outcome of presidential elections than smaller states like Wyoming or Vermont. Additionally, many states have the winner-takes-all system, meaning the winner of the popular vote in the state gets all the electoral votes for that state, this also favors the states with large population. This can lead to a situation where candidates may focus more on winning the support of voters in large population states, rather than trying to gain support from voters in smaller states.