Question

Describe the steps to identify the type of mutation that is caused by sickle cell.

Use the example below to explain your answer:
Normal DNA: TGA GGT CTC CTC
Sickle Cell DNA: TGA GGT CAC CTC

Answer 1

frequent sickness easily getting sick and coughing all the time

Answer 2

To identify the type of mutation in sickle cell, compare the DNA sequences of normal and sickle cell individuals and identify the single nucleotide change. In this case, the mutation is a substitution mutation, where a thymine (T) is replaced by an adenine (A).

Step-by-step explanation:

To identify the type of mutation that causes sickle cell, you can compare the DNA sequence of normal individuals with that of individuals with sickle cell disease. In the example provided, the normal DNA sequence is TGA GGT CTC CTC, whereas the sickle cell DNA sequence is TGA GGT CAC CTC. By comparing these two sequences, we can identify a single nucleotide change.

In this case, the mutation is a substitution mutation, which is when one nucleotide is substituted for another. Specifically, in sickle cell disease, a thymine (T) in the normal DNA sequence is replaced by an adenine (A) in the sickle cell DNA sequence.