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How was penicillin improved?

User Sajee
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Answer:

A number of semisynthetic penicillin derivatives improving the properties of penicillin have been developed since penicillin was first commercialized. Ampicillin, patented by Beecham in 1961, improved the oral absorption of penicillin. Amoxicillin, also patented by Beecham in 1964, further improved oral absorption.

User Kennyc
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