Final answer:
The book 'The Grapes of Wrath' by John Steinbeck describes the impact of the Dust Bowl on farmers in the Great Plains, highlighting the loss of topsoil and the resulting economic and environmental hardships.
Step-by-step explanation:
The book that describes how the Dust Bowl of the 1930s affected farmers of the Great Plains is The Grapes of Wrath. Written by John Steinbeck, this novel is a poignant portrayal of one family, the Joads, who are forced to leave their farm due to the environmental and economic disasters of the Dust Bowl era. Over-farming, drought, and windstorms led to a catastrophic loss of topsoil across the Plains, eroding the ability of farmers to grow crops and sustain their livelihoods. Steinbeck's narrative captures the hardships faced by thousands of families during this time as they struggled with displacement and the search for better opportunities.