Final answer:
The mass of an atom primarily depends on its mass number, which is the sum of the protons and neutrons, and is expressed in atomic mass units (amu).
Step-by-step explanation:
The mass of an atom is determined by the number of protons and neutrons it contains, which is known as the mass number (A). Protons and neutrons both have a mass close to one atomic mass unit (amu), which is defined as one-twelfth of the mass of a carbon-12 atom.
An atomic mass unit is approximately 1.67 × 10-27 kilograms. The mass of an atom can be approximated by its mass number, as electrons contribute negligibly to the overall mass. Therefore, the mass in atomic mass units is nearly equal to the sum of the protons and neutrons in the atom (mass number A).