First let;s solve part (a)
Now first place can be filled in 4 ways
Second place can be filled in 22 ways
Third place can be filled in 21 ways
Fourth place can be filled in 20 ways
Fifth place can be filled in 19 ways
Sixth place can be filled in 18 ways
So total number of 6 letter words will be
(b)
If digits are can be repeated then first pace can be filled in 4 ways but trest of the positions can be filled in 26 way s
So total numbe rof words will be
c) Now first place can be filled in 4 ways
And sixth place can be fille din 1 way only
and no letter can be repeated
So second place can be filled in 21 ways
Third place can be filled in 20 ways
Fourth place can be filled in 19 ways
Fifht place can be filled in 19 ways
So total numbe of words will be
The last part is same as the part (a)