The best answer is B.
If a person is predisposed to a particular disease, they are most likely to catch that disease due to heredity. This is called genetic predisposition.
Genetic predisposition sometimes also called genetic susceptibility, is an increased likelihood of developing a particular disease based on person's genetic makeup.
Genetic predisposition results from some specific genetic variations that are often inherited from parents. These genetic changes contribute to the development of a disease but do not cause it. Some predisposed people will never get the disease while others with same predisposition will get it, even within the same family.