Answer: D) Cancel out.
Step-by-step explanation: The connotation of a word is the meaning given by the context or even by the readers, based on their emotions or personal experiences, it is the antonym of denotation, which is the literal meaning of a word, the one that we can find in a dictionary. In the given excerpt from "Anti-Federalist Paper No. 84" the meaning (or denotation) of the word "counteract" is "cancel out", because counteract is act against something or someone, in order to reduce its force or neutralize it.