Hey there :)
Option TRUE will be the answer.
Reason :-
The environment contributes to determining whether a mutation is advantageous, deleterious, or neutral. Also, the environment or selective pressure determines whether a mutation is beneficial or dangerous.
Usually mutuations are harmless, but in the rarest cases, it can even destroy or affect the whole world.
Example:- From COVID-19's mutation, Deltacron, Florona and Ba12 viruses have evolved.
~Benjemin360