It is a true fact that the loss of an organism at the bottom of a food chain negatively impacts all organisms in the chain.
Explanation:
This is because if the below organism which is constantly interchanged with plants, no herbivores would eat those plants, thus, will also die, which will also determine that the next consumers will have trifle to eat which will also happen to their deaths. So, yes. It concerns it negatively. And very negatively.