Final answer:
OPTION E.
The statement 'Isotopes differ in their nuclear charge' is inconsistent with the concept of isotopes, as isotopes have the same number of protons and hence the same nuclear charge, differing only in their number of neutrons and mass numbers.
Step-by-step explanation:
Isotopes are atoms of the same element that have the same number of protons but different numbers of neutrons. This results in isotopes having the same atomic number but different mass numbers. Given this definition, the statement that is inconsistent with the concept of isotopes would be: e. Isotopes differ in their nuclear charge
Isotopes of the same element have the same number of protons and thus the same nuclear charge; they only differ in the number of neutrons, which affects the mass number, not the nuclear charge. Therefore, isotopes exhibit the same chemical behaviors, even though they have different masses.