Answer:
The sentence that exhibits proper usage is D. Leonardo da Vinci's Mona Lisa is probably the most famous painting in the world.
Step-by-step explanation:
This sentence exhibits proper usage because Mona Lisa, that is a painting, is not between quotation marks. Titles of paintings, drawings, statutes, photographs or any other works of art should not be between quotation marks.
In any case, Mona Lisa could be italicized, like this: Leonardo da Vinci's Mona Lisa is probably the most famous painting in the world.