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Explain the role of calcium ions (Ca2+) in the sliding filament theory of muscle contraction? Explain the importance of the proper function of ATP in this process. Theorize what may happen if there were a breakdown of ATP production.

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Final answer:

Calcium ions initiate muscle contractions by binding to troponin-tropomyosin and exposing actin-binding sites. ATP is crucial for muscle contraction as it provides the energy needed for cross-bridge formation and detachment. A breakdown of ATP production would impair muscle contraction and result in muscle fatigue and weakness.

Step-by-step explanation:

In the sliding filament theory of muscle contraction, calcium ions (Ca2+) play a crucial role. When an action potential reaches the muscle cell, it triggers the release of Ca2+ ions from the sarcoplasmic reticulum. These Ca2+ ions bind to the protein complex troponin-tropomyosin, causing a conformational change that exposes the actin-binding sites on actin filaments.

The proper function of ATP is essential in this process. ATP provides the energy required for muscle contraction. When ATP binds to the myosin heads, it breaks the cross-bridges formed between myosin and actin, allowing myosin to detach from actin and reset for the next power stroke. Without sufficient ATP, muscle contraction cannot occur.

If there were a breakdown of ATP production, muscle contraction would be impaired or cease altogether. ATP synthesis in muscle cells is mainly dependent on cellular respiration, which requires oxygen. Without a sufficient oxygen supply or metabolic dysfunction, ATP production would be reduced, leading to muscle fatigue, weakness, and potentially muscle failure.

User Daniel  Magnusson
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Calcium ions bind to tropomyosin protein which causes a chnage in shape, pulling tropomyosin out of the actin-myosin binding site on the actin filament. It also activated enzyme ATP hydrolase which breaks down ATP to ADP and and inorganic phophate to release energy needed for muscle contraction.

In this process, hydrolysis of ATP (attched to myosin head) causes bending of the myosin head which pulls the actin filament along in a rowing motion.

User Rocketq
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