To answer this question, first
let ∫ √(t³+1) dt = g(t) + C
Then g'(t) = √(t³+1)
F(x) = ∫₀ˣ √(t³+1) dt = g(t) |₀ˣ = g(x) - g(0)
Now g(x) is some function of x, while g(0) is a constant
F(x) = g(x) - g(0)
Differentiate both sides:
F'(x) = g'(x) - 0 = √(x³+1)
So you are correct, in this case, we simply replace t with x (this is not always the case)
F'(2) = √(2³+1) = √9 = 3
You MUST remember that when dealing with square roots, we have:
x² = 4 -----> x = -2 or 2
x = √4 ----> x = 2
That's why in the quadratic formula: x = (-b ± √(b²-4ac)) / (2a), we use a ± sign in front of square root, otherwise, if we could willy-nilly assign positive and negatives value to √(b²-4ac), then we would have no need for the ± sign.
Also, when solving x² = 4, we usually have intermediate step
x = ± √4, where +√4 (or simply √4) = 2, and -√4 = 2