Question

What is meant by the "induced fit” of an enzyme?

Answer 1

The induced fit model describes the dynamic interaction between an enzyme and its substrate, allowing for an ideal binding arrangement by a conformational change in the enzyme's structure.

Step-by-step explanation:

The induced fit model describes the dynamic interaction between an enzyme and its substrate. In this model, as the enzyme and substrate come together, their interaction causes a mild shift in the enzyme's structure, allowing for an ideal binding arrangement between the enzyme and the transition state of the substrate. This conformational change maximizes the enzyme's ability to catalyze the reaction. An example of the induced fit model is when an enzyme's active site molds itself around the substrate to provide an optimal fit.

Answer 2

Induced Fit. When an enzyme binds to the appropriate substrate, subtle changes in the active site occur. This alteration of the active site is known as an induced fit. Induced fit enhances catalysis, as the enzyme converts substrate to product.