What is a significant advantage to the cell in having pyruvate dehydrogenase consist of a large, multi-enzyme complex?

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asked Jun 17, 2017 74.1k views

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ASSILI Taher · Answer 1 · 2017-06-24T11:11:53+0000

Pyruvate dehydrogenase consists of three enzymes: -Pyruvate dehydrogenase, Dihydrolipoyl transacetylase, and Dihydrolipoyl dehydrogenase. The short distance between these enzymes allows channeling of substrates which minimizes the side reactions.

What is a significant advantage to the cell in having pyruvate dehydrogenase consist of a large, multi-enzyme complex?

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