Final answer:
Meiosis differs from mitosis in terms of chromosome number and genetic variation. During meiosis I, homologous chromosomes undergo crossover and separate, resulting in a reduction of the ploidy level. Meiosis II is similar to mitosis, where sister chromatids separate.
Step-by-step explanation:
In meiosis, the number of chromosomes is halved and genetic variation is introduced, while in mitosis, the number of chromosomes remains the same and no genetic variation is introduced.
During meiosis I, homologous chromosome pairs physically meet, undergo crossover, and line up as tetrads along the metaphase plate. The homologous chromosomes then separate, resulting in a reduction of the ploidy level. Meiosis II is more similar to mitosis, where duplicated chromosomes line up on the metaphase plate and sister chromatids separate to opposite poles.