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At what pH values is lipase likely to be denatured? justify your answer

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At pH values above 7, lipase denatures and aggregates when heated at temperatures above 45 degrees C.

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Lipases are likely to be denatured by highly acidic or highly basic pH. Evidence of this is present in the fact that bile is released into the endothelium where the lipases will act in order to neutralize the stomach acids. 
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