Hormones are chemicals from endocrine glands, and neurotransmitters are chemical signals from neurons. Hormones are electric impulses sent from endocrine glands, and action potentials are electric signals sent through neurons. Endocrine glands and neurons both send their messages through the bloodstream. Endocrine glands and neurons both use electrical signals. I think it might the both common is using electric signal. Most neurons have only one axon. An axon is the part of the neuron that transmits nerve signals away from the soma to other neurons ....Endocrine signaling occurs when endocrine cells release hormones that act on distant target cells in the body. Refer to textbook..