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What is a key factor that limits the size of a cell?

What is a key factor that limits the size of a cell?
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What is a key factor that limits the size of a cell?

User Omggs
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The factors limiting the size of cells include: Surface area to volume ratio (surface area / volume) Nucleo-cytoplasmic ratio. Fragility of cell membrane.
User Maksim Vorontsov
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