he plague sprawled from Sarai to Cairo in 1345 though both land and sea. The ports - Alexandria, Genoa, and ports in Sicily and Cyprus were integral in rapidly spreading the diseases in the Mediterranean region where Cairo is found. The plague had its outbreak in 1348. The Black Death traveled to France primarily down the routes like the Rhone valley in 1348. So the years it took it take the Black death to spread from Sarai to Cairo and Paris is 9 years.