202k views
2 votes
Why is the frequency of X–linked disorders greater in males compared to females?

User Sophocles
by
8.7k points

1 Answer

2 votes
Because males possess only a single copy of the X chromosome (genetically, males are XY) whereas females possess two copies of the X chromosome (genetically XX).

As an aside, in case your teacher drops this on you, males receive their X chromosome from their mothers, since the Y chromosome would have to come from their fathers.

Lastly, a female would be considered a "carrier" if only one of her two X chromosomes was associated with an X-linked disorder (one normal X chromosome and one that was associated with the X-linked disorder). Carriers generally are asyptomatic, but pass the abnormal X chromosome to their male children in roughly 50% of cases (since there is a 50-50 chance of their passing the abnormal X chromosome)

Hope this helps!
User Byterussian
by
8.5k points

No related questions found

Welcome to QAmmunity.org, where you can ask questions and receive answers from other members of our community.

9.4m questions

12.2m answers

Categories