Answer:
In 1644, the Virginia Company waged an all-out war against Native Americans, marking the beginning of the Third Anglo-Powhatan War.
Step-by-step explanation:
In 1644, during the reign of Opechancanough, then more than 90 years old, the Indians attacked the settlers of Virginia. More than 500 English were killed, but these settlers accounted for only one-tenth of the total population.
This attack was followed by an unprecedented wave of violence by the British. In July, they march on the villages of Pamunkey and Chickahominy then ravaged the mouth of the James where the Appomattoc, Weyanoke, Warraskoyak, and Nansemond tribes lived, then massacred two other tribes of Carolina, Chowanoke and Secotan.
In February 1645, three new forts were built: Fort Charles downstream of the James, Fort James on the Chickahominy and Fort Royal downstream of the York. In August Governor William Berkeley stormed the last Powhatan Fortress. Opechancanough was captured, brought back to Jamestown and slaughtered. All men over 11 were deported to Tangier Island. This defeat, as well as the loss of their leader, finally broke any fighting spirit on the part of the Powhatans. The English continued to massacre the native tribes, and the confederacy of the Powhatans finally disintegrated. In March 1646, the English built a fourth fort, the Fort Henry on Appomattox. The settlers now controlled the whole area.