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Why do phospholipids form a bilayer in water

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Final answer:

Phospholipids arrange themselves in a bilayer in water due to their amphipathic nature, with hydrophobic tails facing inwards and hydrophilic heads facing outwards, resulting in a stable structure that separates internal and external cellular environments.

Step-by-step explanation:

Phospholipids form a bilayer in water due to their amphipathic nature, which features both hydrophilic (water-attracting) heads and hydrophobic (water-repelling) tails. In an aqueous environment, phospholipids automatically arrange themselves with their hydrophobic tails facing inward and their hydrophilic heads facing outward. This configuration establishes a bilayer, with each layer presenting the hydrophilic heads towards the watery surroundings and shielding the hydrophobic tails from water by placing them in the interior.

The result is a stable structure that forms the basis of cell membranes, contributing to its functionality by separating the water and other materials on one side from those on the other side. When phospholipids are heated in water, they can also spontaneously form micelles or liposomes, which are small spherical structures with hydrophilic heads on the exterior and hydrophobic tails on the inside.

User David Frick
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Phospholipids will form a bilayer in water because they contain hydrophobic (Water fearing.. in this cause water "hating") tails and hydrophilic heads (water loving). So they form a bilayer to remove the tails from water likewise, this satisfies the hydrophilic heads because they are still exposed to water.
User Andrey Rankov
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