there are two vowels in the word 'micro' i and o
so there are 2 possibilities for the first letter slot.
there are 5 slots total and the first slot has been taken so
there are 4 options for the second slot
3 options in the 3rd slot
2 options in the 4th slot
and 1 option in the 5th slot
so 2*4*3*2*1=48 possibilities