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What were two challenges American settles faced when moving west???

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Answer:

They faced danger from indians who were uspeset they were impeding on their land and they faced scarce resources for food, as they passed through the great plains there were barely any animals and they were small and hard to catch

User Hitesh Israni
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Two of the main challenges American settles faced when moving west were 1) A lack of food and shelter (along with harsh winds and rains), and 2) Hostile Natives. 
User Herminio
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