Question

Which genetic mutation would cause the most dramatic change in the genetic make-up of an individual?

A.) A base-pair substitution mutation where one base pair becomes another but codes for the same amino acid.
B.) A gene mutation that inserts one extra base pair into the genetic sequence.
C.) A mutation that deletes three consecutive base pairs from the genetic material.
D.) A single point mutation that changes the codon for a different amino acid.

Answer 1

"A gene mutation that inserts one extra base pair into the genetic sequence" is the genetic mutation that would cause the most dramatic change in the genetic make-up of an individual. The correct option among all the options that are given in the question is the second option or option "B". I hope it helps you.

Answer 2

I believe the most dramatic genetic mutation would be B. Mainly because by inserting an extra base pair you are disrupting the reading frame, thus affecting the primary structure of the polypeptide as it is being synthesized during translation. The codons after the insert will all be different may or may not be coding for different amino acids.