The discovery of BRCA1 and BRCA2 genes led to a new understanding of how genetic mutations increase the risk of cancer is. Mutations in the genes BRCA1 (breast cancer gene 1) and BRCA2 (breast cancer gene 2) increase a woman's risk of developing breast or ovarian cancer. BRCA mutations account for about 5% of all breast cancers and 4%–11% of all ovarian cancers.
The correct answer between all the choices given is the second choice or letter B. I am hoping that this answer has satisfied your query and it will be able to help you in your endeavor, and if you would like, feel free to ask another question.