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Osteoporosis - a chronic, progressive system, metabolic diseases of the skeleton, or a clinical syndrome manifested in other diseases, which is characterized by decrease in bone density, a violation of their microarchitectonics and increased fragility, due to metabolic disorders of bone tissue with a predominance of catabolism of the processes of bone formation, decreased bone strength and increased risk of fractures.This definition refers to osteoporosis diseases of the musculoskeletal system and connective tissue (ICD-10) and completes his term "metabolic or metabolic diseases."