The given substance combusts following the reaction:
C2H2 + (5/2)O2 -> 2CO2 + H2O
Assume C2H2 is an ideal gas. At STP, 1 mol of an ideal gas occupies 22.4 L. Given 100.50 mL of C2H2, this means that there is 4.4866 x 10^(-3) mol. Combusting 1 mol of C2H2 consumes (5/2) mol of O2, then combusting the given amount of C2H2 consumes 0.01121 mol of O2. At STP, this amount of O2 occupies 251.25 mL.