Final answer:
The indigenous inhabitants of the New World viewed interactions with European settlers as harmful primarily because of the deadly diseases brought by the Europeans, to which they had no immunity, leading to widespread death and societal collapse.
Step-by-step explanation:
Many indigenous inhabitants of the New World adopted the view that interaction with European settlers was harmful to their societies due to the impact of new diseases brought by the Europeans. The passage indicates an 'invisible force' that ravaged tribal populations, and historical accounts confirm this refers to epidemics of diseases like smallpox to which the Native Americans had no resistance. This catastrophic loss of life led to the destabilization and collapse of indigenous societies, as their numbers dwindled rapidly in the face of diseases they had never encountered and against which they had no immunity.
The early interactions that included trade and the exchange of goods were initially positive, but the long-term effects were devastating. European colonization and the establishment of different concepts of ownership, the use of military force, and the introduction of commodities and religion further exacerbated the negative perception of European settlers among Native American societies. The Columbian Exchange, while facilitating cultural and economic interactions, ultimately led to immense suffering and demographic catastrophe for indigenous peoples.