Question

Which one of the following statements holds true for the induced-fit model?

a. Once the enzyme binds to the specific substrate molecule, no structural changes can occur in the active site of the enzyme.
b. Once the enzyme binds to the specific substrate molecule, structural changes can occur in the active site to accomodate the product.
c. Once the enzyme binds to a specific substrate molecule, subtle structure changes occur in the active site, which are reverted when the reaction is over.

Answer 1

C. once the substrates bind to the enzyme, the active site of the enzyme changes, to the shape of the substrate. Once the product detaches from the enzyme, then the active site returns to it's normal shape