- The rate limiting reaction of aerobic respiration involves the phosphorylation of fructose phosphate by the enzyme phosphofructokinase.
- The rate at which this enzyme makes product is decreased when adenosine triphosphate (ATP) levels rise because the molecule adenosine triphosphate (ATP) binds to an allosteric site on the enzyme and acts as a direct inhibitor.
- When adenosine triphosphate (ATP) levels fall, AMP binds to the allosteric site of phosphofructokinase.
- This interaction leads to an increase of cellular adenosine triphosphate (ATP), so that this is an example of a negative feedback loop.
What is an aerobic respiration?
An aerobic respiration can be defined as a chemical and biological process that involves the use of oxygen in living organisms to make energy (ATP) from carbohydrates (sugars) during cellular respiration.
This ultimately implies that, an aerobic respiration can take place or occur in the presence of oxygen.
What is an enzyme?
An enzyme can be defined as a biological catalyst that typically speeds up (accelerates) the rate of a chemical reaction, especially by lowering the activation energy of its chemical reactants.
Factors that affects an enzyme
There are four (4) main factors that affect the actions and the rate of an enzyme and these include the following:
- The logarithmic concentration of hydrogen (pH).
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