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Describe nondisjunction and the effect it can have on a human

User Ian Bush
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Answer:

It is the failure of homologous chromosomes to separate properly during gamete formation (meiosis). Klinefelter syndrome can occur and is seen as males with gametes XXY instead of XY. It affects sex organs, including creating smaller testes and causing sterility. Males can be taller in stature with normal intelligence.

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User Winston Smith
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Nondisjunction is the improper segregation of chromosomes during either meiotic or mitotic cell division.

The result of nondisjunction is dosage imbalance - either one extra or one missing chromosome for some proportion of the resulting cells.
User Thomas Buckley
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