You have the following expression:
(2⁸5⁻⁵19⁰)⁻²(5⁻²/2³)⁴2²⁸
In order to simplify the previous expression, consider that any number powered to 0 is equal to 1. Moreover, take into account that a number powered to a number powered to another number is equal to the same number powered to th emultiplication of the expoenents, that is:
(2⁸5⁻⁵1)(5⁻⁸/2¹²)2²⁸ =
(2⁸/5⁵)(1/5⁸2¹²)2²² =
2⁴²/5¹³
Hence, the simplified expression is 2⁴²/5¹³