Answer:
The correct answer would be the first option.
The stimuli receptors receive the stimuli from the external environment which are then passed to the central nervous system (CNS; brain and spinal cord) with the help of sensory or afferent neurons.
The brain or CNS then process and produce the response signals.
These response signals are then passed to the effector organ such as muscle or gland with the help of efferent or motor neurons.
The muscle or gland then produce the response.