Glucose derivatives can produce a number of different molecules, including sugar acids. Below are three sugar acids. (1) Indicate which carbon has been oxidized in glucose to produce the sugar acid and (2) match the function of the sugar acid by selecting the letter associated with a description. This will require you to investigate functions!
a. This sugar acid is used as a substrate in glucuronosylation reactions to modify other insoluble molecules, forming glucuronides that are water soluble and can be more efficiently eliminated from the body as waste. b. Produced in small amounts in mammals, but found in higher amounts in fruits, including apples and grapefruits. This sugar acid has been shown to limit hormone-dependent cancers through inhibition of β-glucuronidase. c. Found in honey, where the pH is kept acidic to inhibit growth of microorganisms. This sugar acid is produced by the enzyme glucose oxidase and serves to enhance flavor.
i. Gluconic Acid: oxidation at __________, function description letter ____ ii. Glucuronic Acid: oxidation at _________, function description letter ____ iii. Glucaric Acid: oxidation at _________, function description letter ____