Question

In his transformation experiments, what did griffith observe?

Answer 1

Griffith's transformation experiments showed that nonpathogenic bacteria could be transformed into pathogenic bacteria through exposure to a heat-killed pathogenic strain. The 'transforming principle' was later identified as DNA.

Step-by-step explanation:

Frederick Griffith's transformation experiments in 1928 showed that live, nonpathogenic Streptococcus pneumoniae bacteria could be transformed into pathogenic bacteria through exposure to a heat-killed pathogenic strain. He concluded that a substance, which he called the 'transforming principle,' had been passed from the dead pathogenic bacteria to the live nonpathogenic bacteria. Later experiments by Avery, MacLeod, and McCarty in 1944 confirmed that the transforming principle was DNA.

Answer 2

Griffith observed that combining a pathogenic strain of bacteria that had been heat killed with a non-pathogenic strain of bacteria that was still alive may cause some of those living bacteria to become pathogenic.
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