Question

What if FGF21? What is FAP? why was it chosen as a potential target for anti-diabetic therapy? what results suggest that this might be problematic, i.e., that the response might not be what was hoped?

Answer 1

FGF21 is Fibroblast Growth Factor 21 and FAP is Fibroblast Activation Protein. It has been said that it can lower blood glucose and raise insulin responsiveness, however, only 40% agreed to it and the rest got additional anti-diabetic agent to provide a better control of glucose levels.