First of all, there are 19 American cities that have populations of over 100,000 with more than 50% of Black or African-American population as the majority. These cities are in the following states of Texas, Virginia, Tennessee, Ohio, New Jersey, Mississippi, Michigan, Maryland, Louisiana, Indiana, Georgia, Florida, and Alabama. Whereas In the State of Texas, the city with the most Black or African-American population in Houston, Texas, which has about 498, 466 Black or African American population.