Final answer:
Motor neuron axons must connect to muscle fibers at a neuromuscular junction, acetylcholine must be released and bind to receptors on the sarcolemma, and depolarization of the sarcolemma must occur to initiate muscle contraction.
Step-by-step explanation:
In order for nerve impulses to stimulate muscle contraction, certain structures of axons and muscle cells must be true:
- Motor neuron axons connect to muscle fibers at a neuromuscular junction: This is a specialized synaptic structure where the axon terminals of motor neurons synapse with the muscle fiber sarcolemma.
- Acetylcholine is released and binds to receptors on the sarcolemma: The synaptic end bulbs of the motor neurons secrete acetylcholine, which binds to receptors on the muscle fiber sarcolemma, causing an increase in movement of cations.
- Depolarization of the sarcolemma initiates muscle contraction: The binding of acetylcholine opens ligand-gated ion channels, which depolarizes the sarcolemma and triggers muscle contraction.