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What was the main conflict between the Ottoman and Safavid empires?

User Nxn
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The area of Mesopotamia, permanently lost to the Ottomans in 1639 is shaded. The Ottoman–Safavid War of 1623–1639 was the last of a series of conflicts fought between the Ottoman Empire and Safavid Persia, then the two major powers of the Near East, over control of Mesopotamia.
User Berry Tsakala
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