Prader–Willi syndrome (PWS) is a hereditary disorder because of loss of function of specific genes. Starting in childhood the individual converts continually hungry which often goes to obesity and type 2 diabetes. So the region of the brain would be best target is the hypothalamus. The hormones from the hypothalamus oversee physiologic purposes such as temperature, dehydration, starvation, sleep, attitude, and the discharge of other hormones within the body.