Centrioles and microtubules have a very close relation to the Micotubule Organizing Center (MTOC), which is involved in the issue on hand. The MTOC is responsible for organizing the centrioles and microtubules, because those organelles will be the ones to pull the chromosomes to the poles of the cell. So, if there is a problem in organizing centrioles and microtubules, they won't connect properly to the chromosomes and won't be able to pull them to the right poles (which is necessary to divide the total amount of chromosomes in order to duplicate the cell). There are no direct relation between those organelles and the vacuole, therefore we can say that A) is incorrect. Those organelles also don't play a decisive role in proteins production, so B) is wrong as well. The mitochondria isn't directly related to centrioles and microtubules also, so D) is also incorrect. Based on the information discussed, the correct answer is c) cells with double the correct amount of chromosomes, because when the chromosomes aren't separated, the cell will maintain the total amount and duplicate it, so it will end up being the double of the correct amount.