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Horses and donkeys can breed and produce sterile offspring known as mules. Horses and donkeys remain separate species because of this hybrid sterility, which is:

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Which is a post-zygotic barrier to reproduction. The postzygotic reproductive barrier is a component that lessens the feasibility or regenerative limit of half-breed posterity. Half-breed zygote variation from the norm is a sort of postzygotic hindrance in which cross breed zygotes neglect to develop regularly.
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