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What are some major obstacles that the colonists faced coming to America?

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Disease, unknown land, natives, and not knowing what crops grow in our soil.
User Greg Kramida
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The first settlers of Jamestown endured the problems of hostile Indians, starvation, and poor leadership and government. Jamestown was the second English Colony in the New World (Roanoke being the first) and the Indians attacked the settlers within 3 days of arrival in May of 1607.
User RecursiveThinking
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